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Closing the loop: A dynamic “sample-to-answer” Ecosystem for vascularized tumor modeling and real-time therapies
Ciro Isidoro 1, Yong Sang Song 2, Danny N Dhanasekaran 3 Introduction Advances in patient-derived organoid technologies have significantly improved our ability to model tumor-specific biology and therapeutic response in vitro. However, most current platforms remain limited…
LncRNAs at the Crossroads of Precision Nutrition and Cancer Chemoprevention
Camelia Munteanu 1, Revathy Nadhan 2, Sabina Turti 1, Eftimia Prifti 1, Larisa Achim 1, Sneha Basu 2 3, Alessandra Ferraresi 4, Ji Hee Ha 2, Ciro Isidoro 4, Danny N Dhanasekaran 1 3 5 Abstract Cancer remains a leading cause of morbidity and mortality worldwide, and effective strategies for cancer prevention are urgently…
Decoding lysophosphatidic acid signaling in physiology and disease: mapping the multimodal and multinodal signaling networks
Revathy Nadhan 1, Karthik Nath 2, Sneha Basu 1 3, Ciro Isidoro 4, Yong Sang Song 5, Danny N Dhanasekaran 6 7 8 Abstract Lysophosphatidic acid (LPA) signaling has emerged as a central regulatory axis in both normal physiology and disease, orchestrating diverse cellular processes such…
SARS-CoV2 e vaccini anti-COVID-19 a mRNA: esiste un plausibile legame meccanicistico con il cancro?
Gentilissime e gentilissimi,condivido con voi la versione in italiano (gentilmente tradotta da Arianna Vocaturo Ciampolillo) del mio articolo “SARS-CoV2 e vaccini anti-COVID-19 a mRNA: esiste un plausibile legame meccanicistico con il cancro?”…
Welcome message of Prof. Ciro Isidoro
Welcome to the Laboratory of Molecular Pathology headed by Prof. Ciro Isidoro.
The laboratory was established in the Department of Health Sciences (formerly Dipartimento di Scienze Mediche) at the Università del Piemonte Orientale "Amedeo Avogadro" in Novara in September 1996.
Our mission is to study the role and the involvement of lysosomal proteolysis in the pathogenesis of diseases. Main areas include:
- The biogenesis and pathophysiological function of Cathepsin D;
- The regulation of the autophagy-lysosomal pathway in cancer and in neurodegeneration;
- The nanobioimaging of vesicular traffic defects.
(Ongoing projects are described in the laboratory and research activities).
Scholars willing to visit our laboratory and students/postDoc who wish graduating or working with us are welcome (please contact us via e-mail).
Aphorisms of your Prof.
In Italia tutto ti è perdonato, fuorché il successo.
cit.- Enzo Ferrari
In Italy everything is forgiven, except for success.
cit.- Enzo Ferrari
Tutti sono necessari e ciascuno è indispensabile.
cit.- Ciro Isidoro
Everyone is necessary and everyone is indispensable.
cit.- Ciro Isidoro
Anela all’ammirazione dei Giusti, ignora l’invidia dei perdenti, rifuggi dalla compassione degli amici.
cit.- Ciro Isidoro
Yearn for the admiration of the Righteous, ignore the envy of the losers, flee from the compassion of friends
cit.- Ciro Isidoro
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Università del Piemonte Orientale Dipartimento di Scienze della Salute (Novara, Italy)
Via Paolo Solaroli, 17,
28100 Novara (NO), Italy
Contact Us
Tel. Office: +39 0321 660507
Tel Lab: +39 0321 660641
Fax: +39 0321 620421
Email: ciro.isidoro@med.uniupo.it
