Tag: cancer

Rita Carini  1, Roberta Castino, Maria Grazia De Cesaris, Roberta Splendore, Marina Démoz, Emanuele Albano, Ciro Isidoro   Affiliation 1 Laboratory of Pathology, Dipartimento di Scienze Mediche, Università del Piemonte Orientale A. Avogadro, via Solaroli 17, 28100 Novara, Italy. PMID: 14970255 DOI: 10.1242/jcs.00923 J Cell Sci. 2004 Mar 1;117(Pt 7):1065-77. doi: 10.1242/jcs.00923. Epub 2004 Feb 17.   Abstract A short period…

Roberta Castino  1 , Marina Démoz, Ciro Isidoro   Affiliation 1 Dipartimento di Scienze Mediche, Università degli Studi del Piemonte Orientale ‘A Avogadro’, Novara, Italy. PMID: 14523947 DOI: 10.1002/jmr.643 Review: J Mol Recognit. Sep-Oct 2003;16(5):337-48. doi: 10.1002/jmr.643.   Abstract Lysosomes and lysosome-related organelles constitute a system of acid compartments that interconnect the inside of the cell with…

Marina Démoz  1 , Roberta Castino, Patrizia Cesaro, Francesco M Baccino, Gabriella Bonelli, Ciro Isidoro   Affiliation 1 Dipartimento di Scienze Mediche, Università A Avogadro, Novara, Italy. PMID: 12437111 DOI: 10.1515/BC.2002.137 Biol Chem. Jul-Aug 2002;383(7-8):1237-48. doi: 10.1515/BC.2002.137.   Abstract In several ‘in vitro’ models of apoptosis, lysosomal proteolysis has been shown to play an active role in mediating the death…

Daniela De Stefanis  1 , Patrizia Reffo, Gabriella Bonelli, Francesco M Baccino, Giuseppina Sala, Riccardo Ghidoni, Patrice Codogno, Ciro Isidoro   Affiliation 1 Dipartimento di Medicina ed Oncologia Sperimentale, Università di Torino, Italy. PMID: 12222689 DOI: 10.1515/BC.2002.106   Abstract Ceramide has been suggested as an important mediator of apoptosis. In HT-29 colorectal cancer cells increased ceramide levels, induced by exogenous N-acetylsphingosine (NAS,…

Roberta Castino  1 , Deborah Pace, Marina Démoz, Marco Gargiulo, Chiara Ariatta, Elisabetta Raiteri, Ciro Isidoro Affiliation 1 Dipartimento di Scienze Mediche, Laboratorio di Patologia Molecolare, Università A. Avogadro, Novara, Italy.   PMID: 11857353 DOI: 10.1002/ijc.10139   Abstract Neuroblastoma is the most common type of cancer in infants. In children this tumor is particularly aggressive; despite various new therapeutic approaches, it…